The Kh-69 has showcased greater range against targets in Ukraine than the 400km stated in Wikipedia. I don't discount JSM, it's just a lighternduty missile, while Kh-69 is basically more closely akin to something like Taurus just in a more suitable form factor (more suitable for the Su-57s and T-75s bays that is), lighter without compromising on warhead weight too much and because of that lacking the penetration on target that Taurus could offer for example.
JSM is good to disable SAM radars and launchers, which makes sense given it's integration into the Joint Strike Fighter, which was primarily developed to conduct SEAD and DEAD against a new generation of Russian and later Chinese origin SAM systems. As Kh-69 is more heavy duty and packs thus more punch, it's obviously more suited to also strike and destroy or severely damage structures, like for example the turbine halls of power plants, or munition stores. My hopes are high that F-47 and F/A-XX will finally be able to carry JASSM and LRASM internally, thus giving the US similar capability with regards to launching stand off munitions covertly without having to mobilize B-2s.