Lasers still expand, the beam isn't perfectly parallel.
And when last I ran the numbers for "range at which beam pointing accuracy times spot size exceeded the size of a 1m target"**, lasers only ended up with a range under 2000km for 200nm (pretty deep UV). IR lasers had an even worse range, down around 300-400km IIRC.
** basically the definition of "effective range of a small arm."
Not really.
Lasers are utterly ineffective until the entire facility is built; power generator, beam generator, and beam pointer.
Missiles are somewhat effective even if you only have a small number of them and their effectiveness increases as you buy more of them.
(I'm assuming that both missiles and lasers will use the same detection gear, so that part of the equation cancels out)
Where's that video of the cutscene in Mass Effect, two dudes getting dressed down for firing before the computer has locked on... "Sir Isaac Newton is the deadliest sumbitch in the galaxy!"