Michel Van said:
where is the advantage of this approach ? ? ?
Primarily reducing the bending moment on the wing. Instead of one very heavy point weight at the middle of the wing, a multi-body design has two or more smaller point weights distributed across the wing. The end result is that either the wing is a lot stonger, or for the same strength it can be a lot lighter. obvious disadvantages are added drag and the need for very wide runways.
In the case of the C-5Z (Zwilling) shuttle carrier, I don't think the improved span loading was a big factor. In it's intended role, the payload (the orbiter) would still be on the centerline and the center wing would be subjected to nearly the same bending loads as a single fuselage layout. The fuselages would probably not be used for payload - with the orbiter aboard, there'd probably be little lifting capacity left. I'd guess that costs would prevent development of capability to carry significant payload in the fuselages without the orbiter aboard. They'd function as really big, really heavy tail booms / landing gear fairings.
The main benefit of the C-5Z approach would have been lowered development costs - it allowed the use of major components without redesign - and a big empty place in the middle. If the fuselages were used without redesign (lightening the structure and reducing drag to exploit the lack of internal payload) the result would probably be less efficient structurally than a properly designed single fuselage design.