Covid-19 Vaccine - Where, How & Costs

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Good information, not fear. Every year, a new flu shot in the US. Swine flu and other variations require it. And what happened to the Zika virus or the West Nile virus?
 
Grey Havoc said:
www.yahoo.com

New clinical trials raise fears the coronavirus is learning how to resist vaccines

Researchers once believed t would take months or even years for the virus to develop resistance to vaccines. The speedy evolution is largely a result of the virus' unchecked spread.
www.yahoo.com www.yahoo.com
Click to expand...

Probably more reason to rapidly vaccinate as many folks as possible while the current vaccines still have better than 50% efficacy. Only way to slow down mutations seems to be to prevent replication and transmission and mass vaccination is probably our best strategy to do that..
 
www.telegraph.co.uk

Ursula von der Leyen attempts to pin blame on deputy for embarrassing U-turn in vaccine export row

The European Commission's chief spokesman said 'only the Pope is infallible'
www.telegraph.co.uk www.telegraph.co.uk

www.telegraph.co.uk

Angela Merkel promises every German a Covid vaccine by autumn after anger at her support for failing EU rollout

Days of anger and finger-pointing have left chancellor under pressure to change tack
www.telegraph.co.uk www.telegraph.co.uk


www.telegraph.co.uk

Ireland 'does not need' vaccines from UK

The country will be covered with supplies from the EU, according to government insiders
www.telegraph.co.uk www.telegraph.co.uk
(Groans)
 
As of early February:
_116751247_optimised-vaccine_doses_per100_countries_most_vax1feb-nc.png
 
www.telegraph.co.uk

One vaccine dose may be enough for people already infected with Covid-19, early studies show

Researchers found that those with prior Covid-19 infections had a high antibody response after one dose of vaccine
www.telegraph.co.uk www.telegraph.co.uk

www.telegraph.co.uk

Sorry not sorry: Ursula von der Leyen refuses to resign over AstraZeneca vaccine row

European Commission president said 'we make mistakes every day' and demanded to be judged in 2024 when her term of office ends
www.telegraph.co.uk www.telegraph.co.uk

www.telegraph.co.uk

Merkel faces tough choices over vaccine procurement amid calls to secure more jabs 'no matter the cost'

Country has faced a shortage despite being the first Western country to develop a vaccine
www.telegraph.co.uk www.telegraph.co.uk
 
www.nytimes.com

Covid-19: Snowstorm Disrupts Vaccinations Across Northeast

The spread of the virus is slowing in U.S. nursing homes. Republican senators who want to scale back aid in the next coronavirus relief package will meet with President Biden.
www.nytimes.com www.nytimes.com

www.nytimes.com

Heavy Snowfall in Northeast Disrupts Travel and Vaccine Rollout

Parts of Pennsylvania and New Jersey received 20 inches of snow. New York City, which got more than a foot, postponed coronavirus vaccinations, but outdoor subway service was resuming at 5 a.m. Tuesday.
www.nytimes.com www.nytimes.com
 
BBC Radio 4 is reporting that the Russian Sputnik vaccine can be used together with the Astraneneca Oxford vaccine and that would increase the ability to cope with variations of Covid. Hope they can cooperate better than the EU has done so far.
 
3na5n22lvmj63her4dozpirpk4--naukatehnika-com.translate.goog

Бразилия намерена купить 30 млн доз российской вакцины Sputnik V и индийской Covaxin

Правительство Бразилии объявило в среду, что ведет переговоры о покупке 30 миллионов доз вакцины против коронавируса в России и Индии после того, как регулирующие органы упростили получение разрешений…
3na5n22lvmj63her4dozpirpk4--naukatehnika-com.translate.goog

"The health ministry said it will meet with representatives from Russia and India on Friday to finalize the details of a deal that will ship about 18 million doses this month and another 12 million in March. The move comes after the medical journal Lancet published results this week showing that the Sputnik V vaccine, named after a Soviet-era satellite, is 91.6 percent safe and effective, allaying concerns about its effectiveness. Brazil began vaccinations on January 17, starting with healthcare workers, indigenous people and the elderly. Brazil, with its 212 million inhabitants, has had an average of 1,062 deaths over the past week and 50,000 cases every day."
 
overscan (PaulMM) said:
A brand new disease never seen by a human population before is one of the sternest tests your immune system will face. It will have to analyse the infectious agent, then produce a unique tailored response to fight it from scratch.
Click to expand...


There is a Belgian study from 2005, well known within the scientific community, which strongly suggests the very deadly "Russian Flu"-pandemic, which started around 1890 and lasted till around 1895, with resurgences till around 1900, was not caused at all by a to humans new Influenza-strain or by an anti-genetic shift (= a sudden very significant mutation) of an among humans existing Influenza-strain, but by HCoV-OC43 ( = Human Coronavirus OC43) which is now one of the 4 (known) human coronaviruses responsible for (only) causing the 'common cold'.
Through genetic sequencing, the researchers investigated HCoV-OC4´s genetic properties and alternations over time to find out when it might have jumped from animalkind to mankind. Their research into HCoV-OC43´s genetic evolution, lead them back to a coronavirus that inhabits cows and a likely animal-to-humans jump around ...1890. So, the severe "Russian Flu" pandemic which started about 1889-1890, might have well been an extremely similar "coronavirus-event" as we are experiencing right now. Also, there were many "neurological symptoms" obversed/described during the Russian Flu pandemic which are rather similar to symptoms seen today with patients suffering from Covid-19.
After many years - maybe a decade or more - the human immune system learned to cope with (H)CoV-OC43 - and vice versa, as the virus mutated and evolved over time and adapted itself to live and multiply within humans without making them severely ill or killing them - and today, 130 years later, it is 1 of the 4 (known) viruses just causing a "common cold".


www.thelancet.com

Taking pandemic sequelae seriously: from the Russian influenza to COVID-19 long-haulers

In January, 1892, the English social reformer and women's rights campaigner Josephine Butler wrote to her son, Stanley, to complain of fatigue and a general declension of the spirits. Butler attributed her symptoms to an attack of “Russian influenza” the previous Christmas, which had left her...
www.thelancet.com

www.nationalgeographic.com

COVID-19 will likely be with us forever. Here's how we'll live with it.

Eventually, the virus could become a much milder illness—but for now, vaccination and surveillance are critical to end the pandemic phase.
www.nationalgeographic.com www.nationalgeographic.com
 
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Death per Millions (last column) and in that order from column 2: 2020 public expenses in percent of GDP, 2020 Debt level (in percent of GDP aswell) and GDP variance:
1612716910717.png
 
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I would hope people follow the recommended precautions. The media in the US is primarily focused on death, followed by the occasional worthwhile item. In the UK, thousands of Pounds in fines have been given out for various gatherings. In the United States, over a million people decided to fly around the Thanksgiving holiday followed by around the same number around Christmas. With near instant global communication, there is no need to look at the 1800s or even the early 1900s.

Another vaccine, this one from Johnson & Johnson, is expected to be approved in the US in a few weeks. 100 million doses have been promised.
 
South-Africa puts on hold all vaccinations with AstraZeneca´s Covid-19 vaccine, because preliminary results show it offers only minimal protection against even mild or moderate infection with the South-African SARS-CoV-2 mutation/strain:

www.reuters.com

South Africa puts AstraZeneca vaccinations on hold over variant data

South Africa will put on hold use of AstraZeneca's COVID-19 shot in its vaccination programme, after data showed it gave minimal protection against mild-to-moderate infection caused by the country's dominant coronavirus variant.
www.reuters.com www.reuters.com
 
Pfizer to cut manufacturing time by two from 110 downto 60 days.
www.nbcnews.com

Pfizer hopes to cut vaccine manufacturing time by almost half

By ramping up production and being more efficient, the company expects to reduce the time it takes to produce a batch of vaccine from 110 days to around 60.
www.nbcnews.com www.nbcnews.com

I also fail to understand the strategy to ship doses in "individual" containers. Since the vaccine is poored from a large container into flacons at the manufacturing site, why not simply organize shipment around barrels (or larger) that can be provided efficiently with a liquid nitrogen cooling units and let cities organize the distribution to the vaccination centers in a hub and spoke architecture (in effect, airports would be the points where vaccine is poored into flacons).
 
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TomcatViP said:
Pfizer to cut manufacturing time by two from 110 downto 60 days.
www.nbcnews.com

Pfizer hopes to cut vaccine manufacturing time by almost half

By ramping up production and being more efficient, the company expects to reduce the time it takes to produce a batch of vaccine from 110 days to around 60.
www.nbcnews.com www.nbcnews.com

I also fail to understand the strategy to ship doses in "individual" containers. Since the vaccine is poored from a large container into flacons at the manufacturing site, why not simply organize shipment around barrels (or larger) that can be provided efficiently with a liquid nitrogen cooling units and let cities organize the distribution to the vaccination centers in a hub and spoke architecture (in effect, airports would be the points where vaccine is poored into flacons).
Click to expand...
I think, amongst other things, it’s probably due to the need to maintain high sanitary control. One mess-up by a city worker trying to dispense the vaccine into the smaller containers needed for vaccination could lead to a lot of illness, maybe deaths, and ineffective vaccination.
 
I doubt that you need a doctorate to work on Pfizer manufacturing line. Pharmacist and lab workers are certainly qualified.
It might come down to having appropriate procedures, tools and quality controls. Neither Clean rooms and automations also are rocket Sciences.
 
starviking said:
I think, amongst other things, it’s probably due to the need to maintain high sanitary control. One mess-up by a city worker trying to dispense the vaccine into the smaller containers needed for vaccination could lead to a lot of illness, maybe deaths, and ineffective vaccination.
Click to expand...
There would also be other logistical and transport issues involved, such as limited or space restricted storage space in some areas.
 
Serbia, all vaccines:
[Serbia] is also speeding ahead of all the 27 EU member states - performing vaccinations at around double the rate of Germany, Spain and Italy and four times the speed of the Netherlands.
Click to expand...
www.bbc.com

How Serbia soared ahead in Covid vaccinations - BBC News

Leaders in this European country do not care where the vaccines come from as long as they are safe.
www.bbc.com www.bbc.com
 
Covid-19 restrictions, England:
Hancock said that from Monday, residents of the U.K. and Ireland arriving in England from the places on the government’s "red list" will have to purchase a "quarantine package" that costs $2,400 per person and covers accommodation, virus testing and other items.
Click to expand...
 
The SA variation is low in number in the UK and the abilty of the AZ vaccine to prevent serious illness is still there. Even moderate variations are going to be unpleasant but so is regular flu. Context folks, it's vital to keep this in context.
 
Dreamfighter said:
overscan (PaulMM) said:
A brand new disease never seen by a human population before is one of the sternest tests your immune system will face. It will have to analyse the infectious agent, then produce a unique tailored response to fight it from scratch.
Click to expand...


There is a Belgian study from 2005, well known within the scientific community, which strongly suggests the very deadly "Russian Flu"-pandemic, which started around 1890 and lasted till around 1895, with resurgences till around 1900, was not caused at all by a to humans new Influenza-strain or by an anti-genetic shift (= a sudden very significant mutation) of an among humans existing Influenza-strain, but by HCoV-OC43 ( = Human Coronavirus OC43) which is now one of the 4 (known) human coronaviruses responsible for (only) causing the 'common cold'.
Through genetic sequencing, the researchers investigated HCoV-OC4´s genetic properties and alternations over time to find out when it might have jumped from animalkind to mankind. Their research into HCoV-OC43´s genetic evolution, lead them back to a coronavirus that inhabits cows and a likely animal-to-humans jump around ...1890. So, the severe "Russian Flu" pandemic which started about 1889-1890, might have well been an extremely similar "coronavirus-event" as we are experiencing right now. Also, there were many "neurological symptoms" obversed/described during the Russian Flu pandemic which are rather similar to symptoms seen today with patients suffering from Covid-19.
After many years - maybe a decade or more - the human immune system learned to cope with (H)CoV-OC43 - and vice versa, as the virus mutated and evolved over time and adapted itself to live and multiply within humans without making them severely ill or killing them - and today, 130 years later, it is 1 of the 4 (known) viruses just causing a "common cold".


www.thelancet.com

Taking pandemic sequelae seriously: from the Russian influenza to COVID-19 long-haulers

In January, 1892, the English social reformer and women's rights campaigner Josephine Butler wrote to her son, Stanley, to complain of fatigue and a general declension of the spirits. Butler attributed her symptoms to an attack of “Russian influenza” the previous Christmas, which had left her...
www.thelancet.com

www.nationalgeographic.com

COVID-19 will likely be with us forever. Here's how we'll live with it.

Eventually, the virus could become a much milder illness—but for now, vaccination and surveillance are critical to end the pandemic phase.
www.nationalgeographic.com www.nationalgeographic.com
Click to expand...

Same for the spanish flu. By 1922, it was old stuff. And God knows how devastating that one had been ! Since then: 1958 and 1968 saw murderous flus, too.
 
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